Health and Medical
Diseases and Conditions
Diabetes
Type 1 Diabetes, AKA Insulin Dependent Diabetes Mellitus (IDDM), or Juvenile Onset Diabetes Melitus
| Type 1 Diabetes, AKA Insulin Dependent Diabetes Mellitus (IDDM), or Juvenile Onset Diabetes Melitus |
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| Written by Jeff Behar | |
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Type 1 diabetes is also referred to as insulin dependent diabetes mellitus
(IDDM), or juvenile onset diabetes mellitus. In type 1 diabetes, the pancreas
undergoes an autoimmune attack by the body itself, and is rendered incapable of
making insulin. Abnormal antibodies have been found in the majority of patients
with type 1 diabetes. Antibodies are proteins in the blood that are part of the
body's immune system. The patient with type 1 diabetes must rely on insulin
medication for survival.
In autoimmune diseases, such as type 1 diabetes, the immune system mistakenly manufactures antibodies and inflammatory cells that are directed against and cause damage to patients' own body tissues. In persons with type 1 diabetes, the beta cells of the pancreas, which are responsible for insulin production, are attacked by the misdirected immune system. It is believed that the tendency to develop abnormal antibodies in type 1 diabetes is, in part, genetically inherited, though the details are not fully understood. Exposure to certain viral infections (mumps and Coxsackie viruses) or other environmental toxins may serve to trigger abnormal antibody responses that cause damage to the pancreas cells where insulin is made. These antibodies can be measured in the majority of patients, and may help determine which individuals are at risk for developing type 1 diabetes. Learn More!!!
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